
Naloxone - WikEM
Pre-mixed nasal spray: 3,4, or 8 mg (1 spray) in one nostril. May repeat q 2-3 minutes if no response. IV/IO: 0.1 mg/kg (max 2 mg). Repeat every 2 to 3 minutes as needed.
Opioid intoxication - EMCrit Project
Sep 15, 2025 · Repeated doses of naloxone or an infusion are required to prevent re-sedation. The usual starting dose for a naloxone infusion is ~2/3rds of the initial cumulative dose …
Naloxone Masterclass – Core EM
Apr 19, 2024 · Determine the “wake-up” dose, the total bolus amount of Naloxone needed to achieve improved respiration. Administer 2/3 of the wake-up dose per hour as a drip (i.e., if a …
Naloxone Drip Dosing - MDCalc
ADVICE Consider gastric decontamination for orally ingested opioid. Look for and remove patches if applicable. The drip may require frequent adjustment based on clinical status.
Naloxone is a competitive antagonist (antidote) to opioid drugs and is used in the treatment of opioid overdose. Its duration of action is shorter than most opioid drugs, so close patient …
When Reversal Turns Risky: Pulmonary Edema After Narcan …
Apr 14, 2025 · Narcan is a cornerstone in the treatment of opioid overdose. It reverses life-threatening respiratory depression, restores consciousness, and often brings dramatic results. …
How and When to Use Naloxone for an Opioid Overdose Naloxone saves lives because it can very quickly restore normal breathing to a person whose breathing has slowed or stopped as a …
Opioid toxicity - WikEM
It has an almost immediate onset of action with a duration of action = 20-90min (depending on the drug ingested, most overdoses especially from heroin will require repeat dosing of Naloxone)
5 Things to Know About Naloxone | Overdose Prevention | CDC
May 2, 2024 · The cost of naloxone varies depending on where and how you get it, as well as your health insurance. People with insurance can check with their insurance company to see …
Narcan - WikEM
Narcan Redirect page Redirect to: Naloxone Retrieved from "https://www.wikem.org/w/index.php?title=Narcan&oldid=33703" Authors: Ross Donaldson